IRAP Therapy

IRAP therapy is designed to block the excessive production of an inflammatory mediator (interleukin-1) in joints affected by arthritis. Osteoarthritis, or degenerative joint disease (DJD) is a significant source of lameness in performance horses. During osteoarthritis,
the cartilage covering the joints is progressively destroyed causing inflammation and pain. Inflammatory mediators in the joint, such as interleukin-1 (IL-1), hasten the destruction of the cartilage and promote inflammation and pain. The intent of IRAP therapy is to block IL-1 from binding to the tissues and causing further damage.

Like PRP, IRAP therapy simply requires a sample of blood from the affected horse. The blood is incubated in a special syringe for twenty-four hours. After incubation, the blood has produced substances that encourage healing, such as growth factors and anti-inflammatory molecules. The blood sample is then centrifuged to separate the red cells from the serum containing these beneficial, therapeutic substances. This serum is then injected into the injured joint, temporarily halting the inflammatory cycle and stimulating healing. Generally, four therapeutic injections are derived from a single blood draw and these are commonly injected at one to two week intervals. The therapeutic serum can be stored for up to six months without loss of efficacy. IRAP therapy seems to provide decent anti-inflammatory results without any of the potential adverse effects of intra-articular steroid administration.


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We invite you to tour our facility in person; please feel free to contact us and we will be happy to arrange a tour for you. Also, there are several photos from our ranch on this website.

Please contact Winners Circle Ranch at:
Phone: (626) 303-7853

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Our Staff

Winner's Circle Ranch would not be what it is today if it weren't for our professional and dedicated staff. We are able to offer the best care and the most advanced veterinary therapeutics because of the people employed at our ranch.
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